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The Promises Treatment Centers, estimates that between five and 10 % of the patients at his doctors are addressed with naltrexone. Those more than likely to receive it are people with a history of early relapse—individuals who have been treated before and also have not had the oppertunity to maintain sobriety for considerably more than four weeks. Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you need to err assisting caution and allow FDA do its job and demand some study be done in order that the public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies are in business to generate income and that they would say almost anything to keep people on his or her medications. Researchers found that participants using this drug for the year, dropped excess weight within one month and have kept the load off through the entire 56 weeks with the study. Contrave is really a combination from the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of many active ingredient, which may make them more efficient and safer. Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular may be the fact that since right now there aren't long term prescription weight loss supplements that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure and heart rate, and must not be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure, along with by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. Other people who should avoid using Contrave are patients being affected by bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave really should not be prescribed for women who are pregnant or attempting to become pregnant.